Is Medical Marijuana The Future Of Breast Cancer Therapy

Is Medical Marijuana The Future Of Breast Cancer Therapy

Statistics show that breast cancer is the most common tumor among women and accounts for 22.9% of all cancers in women across the globe.

In 2008, breast cancer was reported as the cause of over 450,000 deaths worldwide.

CANNABINOIDS AND CANCER

The therapeutic potential of cannabinoids – the medical compounds found in marijuana – in the treatment of cancer has only been discovered recently. Since the late 1990s, numerous preclinical studies have demonstrated the antitumor effects of cannabinoids in a variety of cancers.

Numeorus Studies show that cannabinoid receptors are over-expressed in the tumor cells of certain cancers, such as cancers of the liver, lung, prostate and breast.

Thus, researchers have been led to believe that the endocannabinoid system may be up-regulated in cancer in an innate biological effort to fight off this disease.

Studies also show that when cannabinoids are administered and bind to these receptors, they are able to inhibit cancer cell growth by preventing the proliferation of cancer cells and by inducing cancer cell death (apoptosis).

Furthermore, cannabinoids have been found to impair both tumor angiogenesis – the increase in localized blood flow induced by tumor cells – and metastasis – the spreading of cancer to other organs.

CANNABINOIDS AND BREAST CANCER

There has been great medical advancements in breast cancer in recent decades, but certain breast tumors continue to be resistant to conventional treatments. Breast cancer is comprised of tumors that are distinct in their molecular profiles, leading medical professionals to categorize the disease into 3 main subtypes.

Research suggests that synthetic cannabinoids and phytocannabinoids (mainly THC and CBD) may be useful in treating all 3 subtypes of breast cancer, with the strongest evidence of therapeutic potential pointing to treatment of HER2-positive and triple-negative breast tumors.

The therapeutic potential of cannabinoids is particularly important for patients with triple-negative breast cancer, as there is no standard therapy that currently exists and prognosis for this group of patients is poor.

In addition to their anti-cancer effects, research also shows that cannabinoids are considerably safer and less toxic than conventional treatments. Cannabinoids are non-toxic to non-tumor cells and are well tolerated by patients – only eliciting relatively mild side-effects such as dizziness and fatigue.

“This compound offers the hope of a non-toxic therapy that could achieve the same results without any of the painful side effects.” – Dr. Sean McAllister

In 2007, Dr. Sean McAllister and his team of researchers were one of the first to discover that CBD’s cancer-fighting properties could be successfully applied to breast cancer.

As it turns out, cannabinoids can provide a variety of other benefits in the treatment of cancer, including the prevention of nausea and vomiting associated with standard chemotherapeutic treatments and reduction of cancer-associated pain.

Research also shows that, when combined with conventional cancer treatments, cannabinoids are able to induce a synergistic action against cancer and tumor cells, suggesting that the combination of conventional and cannabinoid-based treatments may more powerful than the administration of either treatment alone.

CLINICAL APPLICATIONS: THE CURRENT STATE

Scientific research on the effects of cannabinoids on breast cancer has been limited to preclinical trials involving cell cultures and animal models.

Researchers believe that further preclinical trials are necessary to identify which patient population is the most appropriate for cannabinoid treatment and which cannabinoids specifically present the best therapeutic option for patients before trials can advance to the clinical stage.

Until these factors are established, it is unlikely that oncologists will be willing to prescribe cannabinoid-based medicine for the treatment of breast cancer, despite the fact that research authors continue to assert the need for health professionals to be aware of cannabinoid research.

See also: One Of The Most Important Scientists In The World: “Most Cancer Research Is Largely A Fraud”

In a recent update (2013) published in the Oncology Nursing Forum, associate editor Susan Weiss Behrend concluded: “…cannabinoids have demonstrated anti tumor activity in preclinical breast cancer models. Practicing oncology professionals need to be aware of the clinical potential of these agents…” – Susan Weiss Behrend, RN

The good thing is that cannabinoid-based pharmaceuticals such as Marinol and Cesamet (oral capsules of synthetic THC) are widely available to cancer patients for the treatment of chemotherapy-induced nausea. As well, Sativex (a natural-cannabinoid derived mouth spray) has been approved in Canada for the treatment of cancer-associated pain.

As modern cannabinoid research flourishes and continues to provide strong evidence of the cancer-fighting effects of these compounds, patients should remain optimistic about the future of cancer research and the emerging role of marijuana-based treatments that may one day take center stage in the battle against this devastating disease.


Sources:

http://www.truthonpot.com/2013/03/22/the-endocannabinoid-system-an-overview/

http://news.bbc.co.uk/2/hi/health/7098340.stm

http://www.ncbi.nlm.nih.gov/pubmed/23448745

Find us here

Get news from the CSGLOBE in your inbox each weekday morning

The views and opinions expressed in this article are those of the authors/source and do not necessarily reflect the position of CSGLOBE or its staff.

Paid content

Fluoride and the Pineal Gland

A Fluoride-Free Pineal Gland is More Important than Ever There has been some controversy over the activity of adding synthetic fluoride to municipal water supplies...

Disturbing: Researchers Finally Confirm That Cancer Is A Purely Man-Made Disease

Researchers from the University Of Manchester, United Kingdom, have concluded that cancer is a purely modern, man-made disease. In the United Kingdom alone, Cancer claims...

Monsanto and Bayer are Maneuvering to Take Over the Cannabis Industry

It has been rumored for years that Monsanto plans to take over the cannabis industry with genetic engineering just as they’ve taken over the...

What's New Today

Georgia House Votes To Allow Citizens To Abolish Police Departments In The State

The Georgia House backed an effort on Friday to dissolve the Glynn County Police Department and any...

Leaked CDC document contradicts Pence claim that U.S. coronavirus cases ‘have stabilized’

Even as Vice President Mike Pence wrote in a Wall Street Journal op-ed published Tuesday that coronavirus...

Five bombshells about Trump from Bolton ‘s book

Excerpts from former national security adviser John Bolton ’s book about his time in the Trump administration...

Don’t Listen to Fox. Here’s What’s Really Going On in Seattle’s Protest Zone.

It seems I live in a city undergoing a “totalitarian takeover” that will lead to “fascist outcomes”...

MOST READ

What Is Agenda 21? Depopulation of 95% of the World By 2030

Most people are unaware that one of the greatest threats to their freedom may be a United Nations program which plans to depopulate 95%...

Complete List of BANKS Owned/Controlled by the Rothschild Family

What’s the significance of having a central bank within a country and why should you concern yourself, your family and colleagues? Central banks are illegally...

Georgia House Votes To Allow Citizens To Abolish Police Departments In The State

The Georgia House backed an effort on Friday to dissolve the Glynn County Police Department and any...

Fluoride and the Pineal Gland

A Fluoride-Free Pineal Gland is More Important than Ever There has been some controversy over the activity of adding synthetic fluoride to municipal water supplies...

Stress: The Modern Poison

Stress: The Modern Poison That is Making Us Fat, Bald, Crazy and Extremely Unhealthy The term stress is tossed around freely in this modern age...

What Happens To Our Body After Drinking Coca Cola?

Have you ever wondered what exactly Coca Cola is? After 10 minutes: Ten tea spoons of sugar contained in a glass of Cola, cause devastating...

Chinese Herb kills cancer cells 10X better than chemo

Today, odds are that you have had/have cancer, or know somebody who does. In Canada, approximately one million Canadians that were alive at the...

Type 2 Diabetes: Blame Added Fructose?

Added fructose is a principal driver of type 2 diabetes, experts argue Recent studies have shown that added sugars, particularly those containing fructose, are a...

Life on Mars? It could be on Earth

Perhaps the greatest irony in the search for alien life was that seekers needed look no further than the mirror. That’s according to a...

Why am I so fat?

This is the question many Americans are asking themselves these days. Why am I so fat? The answer lies in a combination of issues,...

WORLD EXCLUSIVE: Jack the Ripper unmasked

How amateur sleuth used DNA breakthrough to identify Britain's most notorious criminal Jack the Ripper, 126 years after string of terrible murders It is the...