Grape seed extract kills colorectal cancer cells

Researchers from the University of Colorado Cancer Center have just published a study in the journal Cancer Letters that shows grape seed extract (GSE) is a powerful weapon against colorectal cancer. It halts the growth and survival of colorectal cancer cells and kills them in large numbers, too, while leaving healthy cells completely alone.

The power of grape seed extract seems quite remarkable in this research: the more advanced the colorectal cancer cells, the more GSE shuts down the malignant cells’ growth and survival. The scientists think that GSE targets colorectal cancer by causing oxidative stress that leads to the programmed cell death known as apoptosis.

Molly Derry, doctoral candidate in the lab of Rajesh Agarwal, PhD, investigator at the CU Cancer Center and professor at the Skaggs School of Pharmacy and Pharmaceutical Sciences explained:

We’ve known for quite a while that the bioactive compounds in grape seed extract selectively target many types of cancer cells. This study shows that many of the same mutations that allow colorectal cancer cells to metastasize and survive traditional therapies make them especially sensitive to treatment with GSE.

Derry pointed out that the GSE findings are especially important due to the increasing rates of colorectal cancer. Unfortunately, 60 percent of patients diagnosed with this form of cancer have already reached the advanced stage of the disease.

As the research team performed their experiments on colorectal cancer cell lines representing all stages of the disease, they came up with another startling finding. Although it usually takes much more chemotherapy to kill a stage IV cancer cell than a stage II cancer cell, the exact opposite was true when it came to grape seed extract.

It required less than half the concentration of GSE to suppress cell growth and kill 50 percent of stage IV cells than it did to achieve similar results in the stage II cells, Derry revealed in a media statement.

A colorectal cancer cell can have upwards of 11,000 genetic mutations — differences from the DNA in healthy cells. Traditional chemotherapies may only target a specific mutation and as cancer progresses more mutations occur. These changes can result in cancer that is resistance to chemotherapy. In contrast, the many bioactive compounds of GSE are able to target multiple mutations. The more mutations a cancer presents, the more effective GSE is in targeting them, Derry added.

The Agarwal Lab studies the effectiveness and action of dietary compounds against cancer and is encouraging further exploration of their findings in clinical settings with patients. Finding a way to selectively target advanced colorectal cancer cells could have major clinical importance, Derry stated.

As NaturalNews previously reported, researchers from the University of Kentucky have also conducted groundbreaking research into the anti-cancer properties of grape seed extract. They found the natural substance triggered the death of 76 percent of leukemia cells exposed to the extract in a laboratory experiment. Their study, published Clinical Cancer Research, a journal of the American Association for Cancer Research, showed that grape seed extract triggered the destruction of leukemia cells by apparently “turning on” a protein known as JNK that regulates the cancer cell killing pathway.
[divider]

Amazing Grapes

With only 100 calories per cup, grapes are a great source of vitamins K and C and are loaded with antioxidants. Grape seed extract is made from the seed of the grape and is beneficial for a number of cardiovascular conditions such as poor circulation and high cholesterol. The extract has also been found useful in the treatment of diabetes-related eye disease, loss of vision due to aging, and swelling associated with injury. Currently, GSE is being studied in the treatment of leukemia and Alzheimer’s disease.

Source
naturalsociety.com
thewatchers.adorraeli.com
www.cancerletters.info/article/S0304-3835(12)00732-X/abstract

 

Find us here

Get news from the CSGLOBE in your inbox each weekday morning

The views and opinions expressed in this article are those of the authors/source and do not necessarily reflect the position of CSGLOBE or its staff.

Paid content

Europe BANS Food Dyes due to ADHD & Cancer Links

  “FDA examines links between food dyes and hyperactivity in children”  The Associated Press. Ok, so here we go again.  Are food dyes safe or are...

“Magic” Mushrooms Cure PTSD and Even Grow Brain Cells

Psychedelic Mushroom Compound Found to Grow and Repair Brain Cells You may know them as “shrooms”, “Magic mushrooms”, psilocybic mushrooms, or you may not know...

Be Advised! Aspartame Changed its Name to AminoSweet

Aspartame has been renamed -  AminoSweet - and is now being marketed as a natural sweetener Aspartame, the artificial sweetener linked to cancer, heart palpitations,...

What's New Today

Georgia House Votes To Allow Citizens To Abolish Police Departments In The State

The Georgia House backed an effort on Friday to dissolve the Glynn County Police Department and any...

Leaked CDC document contradicts Pence claim that U.S. coronavirus cases ‘have stabilized’

Even as Vice President Mike Pence wrote in a Wall Street Journal op-ed published Tuesday that coronavirus...

Five bombshells about Trump from Bolton ‘s book

Excerpts from former national security adviser John Bolton ’s book about his time in the Trump administration...

Don’t Listen to Fox. Here’s What’s Really Going On in Seattle’s Protest Zone.

It seems I live in a city undergoing a “totalitarian takeover” that will lead to “fascist outcomes”...

MOST READ

What Is Agenda 21? Depopulation of 95% of the World By 2030

Most people are unaware that one of the greatest threats to their freedom may be a United Nations program which plans to depopulate 95%...

Alien Base for Giants Discovered in the Bucegi Mountains

In the summer of 2003, in an unexplored area of the Bucegi Mountains, a team from Zero Department (a top secret section of the...

Putin has Banned Rothschild and His New World Order Banking Cartel Family from Entering Russian Territory

As of recently, Russian president Vladimir Putin took yet another decision for his country. "Under any circumstances", the Rothschild family is banned from entering Russian territory. Along...

Europe BANS Food Dyes due to ADHD & Cancer Links

  “FDA examines links between food dyes and hyperactivity in children”  The Associated Press. Ok, so here we go again.  Are food dyes safe or are...

Sugar is as dangerous as alcohol and tobacco

Doctors Warn Sugar Health Risk as Bad as Tobacco And Alcohol Britain's obesity crisis could be reversed within five years if food companies reduced sugar...

Subway Under Fire Over “Chicken”

In 2014, Subway faced widespread backlash when it was revealed that the bread in their sandwiches contained a chemical commonly found in yoga mats...

Major Corporation Calling GMOs ‘All Natural’

Did you know that your Heinz ketchup, which the company claims is ‘all natural,’ is really full of toxic, genetically modified ingredients? It’s bursting with...

Monsanto responsible for monarch butterflies massacre

Do We Save the Monarch Butterfly or Monsanto's Profits? Ninety percent of our beautiful monarch butterflies have been wiped out, yet it is still has...

Russia and China Prepare for Global War

Both countries want peace, not war. America threatens them. Defensive readiness is prioritized. Forewarned is forearmed. NATO’s a global alliance. Washington heads it. It’s...

THIS IS WHY JESSE VENTURA IS NOT ALLOWED ON LIVE TV! “Every War Starts With A False Flag Operation”

This is just… wow. I wonder what would happen if CNN or Fox or any of the corrupt establishment media had a huge debate...

37 Million Bees Instantly Dropped Dead After Farms Started Spraying Neonicotinoids On GMO Crops

After nearby farms began spraying insecticides on their GMO crops, 37 million bees died instantly at one farm as a result. It’s no secret that...