First magic mushroom depression trial hits stumbling block

The world’s first clinical trial designed to explore using a hallucinogen from magic mushroom’s to treat people with depression has stalled because of British and European rules on the use of illegal drugs in research.

David Nutt, president of the British Neuroscience Association and professor of neuropsychopharmacology at Imperial College London, said he had been granted an ethical green light and funding for the trial, but regulations were blocking it.

“We live in a world of insanity in terms of regulating drugs,” he told a neuroscience conference in London on Sunday.

He has previously conducted small experiments on healthy volunteers and found that psilocybin, the psychedelic ingredient in magic mushrooms, has the potential to alleviate severe forms of depression in people who don’t respond to other treatments.

Following these promising early results he was awarded a 550,000 pounds ($844,000) grant from the UK’s Medical Research Council to conduct a full clinical trial in patients.

But psilocybin is illegal in Britain, and under the United Nations 1971 Convention on Psychotropic Substances it is classified as a Schedule 1 drug – one that has a high potential for abuse and no recognized medical use.

This, Nutt explained, means scientists need a special license to use magic mushrooms for trials in Britain, and the manufacture of a synthetic form of psilocybin for use in patients is tightly controlled by European Union regulations.

Together, this has meant he has so far been unable to find a company able to make and supply the drug for his trial, he said.

“Finding companies who could manufacture the drug and who are prepared to go through the regulatory hoops to get the license, which can take up to a year and triple the price, is proving very difficult,” he said.

Nutt said regulatory authorities have a “primitive, old-fashioned attitude that Schedule 1 drugs could never have therapeutic potential”, despite the fact that his research and the work done by other teams suggests such drugs may help treat some patients with psychiatric disorders.

Psilocybin – or “magic” – mushrooms grow naturally around the world and have been widely used since ancient times for religious rites and also for recreation.

Researchers in the United States have seen positive results in trials using MDMA, a pure form of the party drug ecstasy, in treating post-traumatic stress disorder.

“What we are trying to do is to tap into the reservoir of under-researched illegal drugs to see if we can find new and beneficial uses for them in people whose lives are often severely affected by illnesses such as depression,” Nutt said.

The proposed trial would involve 60 patients with depression who have failed two previous treatments.

During two or three controlled sessions with a therapist, half would be given a synthetic form of psilocybin, and the other 30 a placebo. They would have guided talking therapy to explore negative thinking and issues troubling them, and doctors would follow them up for at least a year.

Nutt secured ethical approval for the trial in March.

In previous research, Nutt found that when healthy volunteers were injected with psilocybin, the drug switched off a part of the brain called the anterior cingulate cortex, which is known to be overactive in people with depression.

“Even in normal people, the more that part of the brain was switched off under the influence of the drug, the better they felt two weeks later. So there was a relationship between that transient switching off of the brain circuit and their subsequent mood,”, he said. “This is the basis on which we want to run the trial.”

By Kate Kelland | REUTERS

 

Find us here

Get news from the CSGLOBE in your inbox each weekday morning

The views and opinions expressed in this article are those of the authors/source and do not necessarily reflect the position of CSGLOBE or its staff.

Paid content

Putin has Banned Rothschild and His New World Order Banking Cartel Family from Entering Russian Territory

As of recently, Russian president Vladimir Putin took yet another decision for his country. "Under any circumstances", the Rothschild family is banned from entering Russian territory. Along...

The End Of The (Petro)Dollar? Venezuela is Paying Iran In Gold For Help

With cash levels dwindling and its once mighty oil sector on its knees and needing help desperately,...

Georgia House Votes To Allow Citizens To Abolish Police Departments In The State

The Georgia House backed an effort on Friday to dissolve the Glynn County Police Department and any...

What's New Today

Georgia House Votes To Allow Citizens To Abolish Police Departments In The State

The Georgia House backed an effort on Friday to dissolve the Glynn County Police Department and any...

Leaked CDC document contradicts Pence claim that U.S. coronavirus cases ‘have stabilized’

Even as Vice President Mike Pence wrote in a Wall Street Journal op-ed published Tuesday that coronavirus...

Five bombshells about Trump from Bolton ‘s book

Excerpts from former national security adviser John Bolton ’s book about his time in the Trump administration...

Don’t Listen to Fox. Here’s What’s Really Going On in Seattle’s Protest Zone.

It seems I live in a city undergoing a “totalitarian takeover” that will lead to “fascist outcomes”...

MOST READ

What Is Agenda 21? Depopulation of 95% of the World By 2030

Most people are unaware that one of the greatest threats to their freedom may be a United Nations program which plans to depopulate 95%...

Putin has Banned Rothschild and His New World Order Banking Cartel Family from Entering Russian Territory

As of recently, Russian president Vladimir Putin took yet another decision for his country. "Under any circumstances", the Rothschild family is banned from entering Russian territory. Along...

Scientists Discover A Second Brain In Human Body, And It’s Located In The Butt

It turns out those gut feelings or pits in your stomach may actually come from your second...

Putin has Banned Rothschild and His New World Order Banking Cartel Family from Entering Russian Territory

As of recently, Russian president Vladimir Putin took yet another decision for his country. "Under any circumstances", the Rothschild family is banned from entering Russian territory. Along...

Farmer Charged, Fined $2.8 Million, For Plowing His Own Property

The US Army Corps of Engineers and state authorities are seeking almost $3 million in fines from a California farmer because residue from plowing...

‘Ready for WAR’ Kim Jong-un promises ‘POWERFUL RESPONSE’ after US Navy deployment to Korea

Kim Jong-un’s state-owned news agency KCNA claimed Trump’s deployment showed “reckless moves for invading” that had now “reached a serious phase”. It comes after Trump...

Fishing trawler crew discover terrifying prehistoric shark with 300 TEETH among their catch

The origin of the shark dates back 80 million years and is eel-like in shape A group of fishermen got quite a shock when they...

Oregon tuna radiation triples since Fukushima

Radiation level in tuna off Oregon coast tripled after Fukushima disaster While the state of Oregon gears up to test its shores for radioactive contamination...

Asia’s First-Ever Vertical Forest Will Produce 132 Pounds Of Oxygen Each Day

When Stefano Boeri Architetti presented the idea of installing a vertical forest in Milan, people were beyond thrilled with the idea. Following the success of...

Tesla’s Ultra-Speed Hyperloop Transportation System Will Change Transportation As We Know It

Billionaire entrepreneur Elon Musk has revealed more information on his top-secret Hyperloop, a vehicle he says will take passengers from Los Angeles to San...

Globalists Are Now Openly Demanding New World Order Centralization

I have said it many times in the past — when elitist criminals start openly admitting to their schemes it means that they are ready...